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Conversely, augmented ferroptosis may sensitize aggressive forms of liver cancers (e.g., HCC, et al.) in conventional chemotherapy regimens

The expression levels of phosphorylated Janus kinase 2 (pJAK2) and phosphorylated signal transducer and activator of transcription 3 (pSTAT3) are elevated in liver tissue [117]

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On the contrary, oral administration of BCAA granules to patients with advanced cirrhosis resulted in a significant increase in IFN- levels, which alleviated the deterioration of the disease caused by impaired DCs function, providing evidence for nutritional therapy with amino acids (108)