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The side effect profile is not dramatically worse than existing options in the class, and the efficacy clearly exceeds them

Insulin, sulfonylureas, narrow-therapeutic-window medications, and any drug where absorption timing matters are all worth flagging

Watch appetite rather than the scale early, treat flat weeks as normal, understand that the plateau is the destination rather than a fault, and go in knowing this is long-term management

The COA and labeling made that simple for our internal records. Hannah Kim Fast dispatch, clean packaging, and no damaged vials

doi:10.1016/j.jaad.2025.01.046

However, when used in combination with other diabetes medications, the risk may increase