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Moreover, LC administrated for 2 weeks suppresses atrogin-1 messenger RNA (mRNA) level in suspended rats hindlimb [35], and only 7 days of LC administration downregulates MuRF-1 and atrogin-1 mRNAs reducing muscle wasting in a rat model of cancer cachexia [32]
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125 MonteroJ.MariM.ColellA.MoralesA.BasanezG.Garcia-RuizC.et al (2010)
However, the broader clinical use of these cells, particularly for autologous transplantation, is often constrained by challenges such as limited availability, invasive harvesting procedures, and complex sourcing processes