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Many preclinical studies have demonstrated that the expression of key enzymes for GSH synthesis (GCL, SLC7A11, GS) and GSSG reduction-related enzymes (G6PD, NADPH, and GR) is downregulated in myocardium exposed to pathological factors [40, 43,44,45,46,47,48,49,50]

It possesses several pharmacological activities, including the ability to effectively scavenge superoxide radicals and act as an immunomodulator, anti-inflammatory, antioxidant, antihypertensive, and anti-carcinogenic (Nafees et al

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