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Semaglutide activates GLP-1 receptors in the pancreas, gut, and hypothalamus to reduce appetite, slow gastric emptying, and improve glycemic control

Patients should carry glucose monitoring supplies and know their target blood glucose ranges

If the trend holds, it could signal a fundamental shift in how Americans eat, and a serious challenge for food giants that spent the past decade gorging on decadent snack acquisitions. Why Dining Rooms Are Disappearing From American Homes (The Atlantic): Eating is relegated to couches and bedrooms, and hosting a meal has become virtually impossible

Their small size renders them simpler to synthesize and modify

5.10 Hyperammonemia and Encephalopathy Associated with Concomitant Topiramate Use Concomitant administration of topiramate and valproate has been associated with hyperammonemia with or without encephalopathy in patients who have tolerated either drug alone