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(8) Matthew G Engel, Sushma Narayan, Min-Hui Cui, Craig A Branch, et al (2025) Intranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice Journal of Alzheimers Disease, 2025 Jan, Volume 103 (Issue 1), Pages 113-126

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Astrocytes are neural parenchymal cells that proliferate after injury to replace lost neural tissue, form borders, and protect and preserve neural parenchyma in different disorder contexts as discussed in multiple places in this article

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Most of the studies focus on the bacterial component (128), but the fungal, viral, and other parts of the ecosystem are almost neglected (129)