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Appetite Regulation and Neuroendocrine Interactions GLP-1 peptides act on neurons in the hypothalamus and brainstem , especially in the arcuate nucleus and nucleus tractus solitarius

29 A short half-life is often problematic with neuropsychiatric medications because rapid washout can be associated with drug withdrawal symptoms as with benzodiazepines or with drug discontinuation syndromes as with antidepressants

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Together, these examples demonstrate how tripeptide-based approaches can modulate inflammation, proliferation, and remodeling to accelerate wound healing