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For plasma biochemical profiles analysis, overnight fasting blood samples were obtained and centrifuged at 3000 r.p.m

The strongest evidence has been obtained for gastric, esophageal, renal and bladder cancers

Prospective studies and randomized trials are currently underway to generate more sophisticated data for inclusion within the screening pathway (203)

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These limitations underscore the need for cautious interpretation and continued, well designed scientific investigation