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459,460,461 Clinical studies show that 47% of elderly heart failure patients have reduced transferrin saturation, and low transferrin saturation is independently linked to a higher risk of all-cause death

In summary, AST demonstrates promising therapeutic potential in PD by targeting key pathological mechanisms such as oxidative stress, neuroinflammation, and mitochondrial dysfunction

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FIGURE 1 In this view, trials aimed at testing the potential repositioning of these compounds should be designed by also taking into account the mechanism of action of single drugs and potential combination with other drugs or molecules

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