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Patients harboring SNCA mutations often present a rapidly progressive disease course, with pathological features that overlap with those of multiple system atrophy and Lewy body dementia

25% [5] (RCT) 6

Many people are interested in understanding the benefits and potential risks associated with these drugs, especially since they are not initially developed for weight loss

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Berg CP, Engels IH, Rothbart A, Lauber K, Renz A, Schlosser SF, et al

This paper is thus conclusive in demonstrating that tirzepatide is associated with a risk of worsening of pre-existing DR but protective against developing any new DR or DME