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Low blood sugar A headache can be a symptom of low blood sugar, which can be more likely when taking glucose-lowering medications like semaglutide especially if you are taking semaglutide in combination with insulin or sulfonylureas (which also lowers blood sugar)

Tirzepatide activates GIP and GLP-1 receptors in the exocrine pancreas, promoting a reduction in blood glucose levels and aiding in the management of type 2 diabetes (T2D) [1]

6X18: Zhang X, Belousoff MJ, Zhao P, Kooistra AJ, Truong TT, Ang SY, Underwood CR, Egebjerg T, enel P, Stewart GD, Liang YL, Glukhova A, Venugopal H, Christopoulos A, Furness SGB, Miller LJ, Reedtz-Runge S, Langmead CJ, Gloriam DE, Danev R, Sexton PM, Wootten D

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Ill be having surgery Many healthcare providers recommend stopping semaglutide at least one week before surgery, sometimes longer, depending on the type of procedure

doi: 10.1007/s40262-017-0528-2