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When PI3K and its regulatory proteins, p85 and p110, are recruited by IRS, they will further recruit and activate PDK1 (PIP 3 -dependent kinase 1), Akt (PKB), mTORC2, S6 kinases and PKC

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Glutathion wirkt als Hauptregulator, indem es reaktive Sauerstoffspezies (ROS) neutralisiert und NF-B hemmt, einen Proteinkomplex, der Entzndungen auslst

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The concentrations of carnosine in the olfactory bulb of the brain and the cardiac muscle are comparable to those in skeletal muscle, but those in other tissues (e.g., ~ 0.1 mM in kidneys and adipose tissue) are only 0.1% to 10% of those in skeletal muscle