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In several multi-center longitudinal studies involving hemodialysis cohorts, the administration of IV Levocarnitine demonstrated a significant reduction in the ESA Resistance Index. Numerical data from recent trials indicates: Anemia Management: Patients receiving IV Levocarnitine showed an average 15% to 25% reduction in the required dose of Erythropoietin (EPO) to maintain target hemoglobin levels

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Eur Neuropsychopharmacol 2 : 4349 Muscat R, Sampson D, Willner P

The EU's Scientific Committee on Consumer Safety (SCCS) said the mouse findings might point to a concern but they're hard to apply to humans since hairless mouse skin and human skin behave differently