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Research protocols use 0.1-0.3 mg per dose, administered subcutaneously in the evening

Johns Wort is known to increase the enzyme activity 3 in the liver that metabolizes hormones in birth control pills, potentially reducing their effectiveness 4 and leading to unexpected pregnancy

The process of mixing these two is called reconstitution, and it's a critical step in proper drug administration

Recombinant GSTP1-1 reference was obtained from earlier study in our group (Zhang et al., 2017a)

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