While they share a common mechanism of action, enhancing glucose-dependent insulin secretion, reducing glucagon secretion, and slowing gastric emptying, there are notable differences in their efficacy and usage in weight management
For a minority, particularly those with pre-existing imbalances in serotonergic function, the shift could theoretically contribute to anxiety symptoms
10.2217/rme.12.112
No embryotoxicity or teratogenicity was seen in animals that received orlistat at doses much higher than the recommended human dose
doi: 10.1007/s11136-021-02808-2
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