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HFD and MCDD feeding experiment Fifteen 4-week-old healthy male GSTM2 knockout mice and 15 wild-type mice were selected for high-fat diet (HFD) feeding

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The assumption of normality was assessed before conducting parametric tests to ensure the validity of the results

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Acknowledgments We acknowledge the contributions of specific colleagues, institutions, or agencies that aided the efforts of the authors

The overall mitochondrial ROS burden thus surpasses the neutralizing capacity of the increased SOD2, rendering these tissues more susceptible to oxidative stress