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Glutathione operates in the cytoplasm and mitochondria, scavenging free radicals that would otherwise oxidise cellular proteins, including growth hormone receptors themselves
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Consequently, the proportion of the more reactive thiolate form is higher in cysteinylglycine than in GSH at the physiological pH value: the reduction rate of ferric ions to ferrous ions is higher, and the production of hydroxyl radicals and superoxide anions through Fenton and HaberWeiss reactions is more abundant
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