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Studies in the nematode Caenorhabditis elegans indicate that the somatic gonad generates an unknown signal to trigger a complex signalling network in other tissues to promote longevity when the germline is removed (Antebi, 2013

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Additionally, future studies should investigate the long-term effects of microbiome-based interventions and explore the potential of personalized medicine approaches tailored to individual patients gut microbial profiles (Cunningham et al., 2021)

Lancet (1975) 1(7897):146

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