PloS One (2020) 15(6):e0235118
We understand the power that lies behind lifestyle, and lifestyle is nothing more than SELF [sleep, exercise, love, and food]
Bian: No
The article says DPP-4 inhibitors such as sitagliptin, saxagliptin and linagliptin block the enzyme that breaks down the incretin hormones GLP-1 and GIP, which raises native GLP-1 levels in the bloodstream
The MGBA represents a bidirectional communication network between the central nervous system (CNS), enteric nervous system (ENS), and gut microbiota, transmitting signals through neural pathways (vagus nerve), endocrine pathways [hypothalamic-pituitary-adrenal (HPA) axis], immune pathways (cytokines, inflammatory mediators), and metabolic pathways [short-chain fatty acids (SCFAs), neurotransmitter precursors] (Loh et al., 2024
But it might make you feel uncomfortable if you eat too much at once