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But glucagon receptor activation also stimulates energy expenditure and fat oxidation in the liver

In fact, this could lead to an increased risk of side effects, such as nausea, vomiting, low blood sugar, and other complications

Body weight is a poor proxy for health

While this is the case for most new medicines, its particularly important for those that work on several hormone pathways simultaneously

In contrast, in human clinical trials with semaglutide or tirzepatide, about 60% of patients achieve a 20% reduction in weight and can keep that weight off with continued use

Universidad de Barcelona, Spain Despite recent advancements in the field of neuro-ophthalmology, the rising rates of neurological and ophthalmological conditions, mismatches between supply and demand of clinicians, and an aging population underscore the urgent need to explore new therapeutic approaches within the field