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In a controlled, open trial with psoriasis patients, secukinumab did not cause liver enzyme elevations, while methotrexate led to a threefold increase in liver enzymes in 4 of 64 patients, necessitating withdrawal (Gisondi et al
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Understanding the relationship between tirzepatide and skin healthincluding potential indirect mechanisms, management strategies, and when to seek medical evaluationhelps patients navigate treatment confidently while maintaining optimal dermatologic care
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