It is my personal thinking that this is one reason behind the common incidence of low to equivocal Lyme titers
Since it is such a strong base, a deprotonated amine (confusingly also called an amide, or sometimes metal amide base) is pretty much the opposite of a decent leaving group
Various substances have been examined as enhancers, with regularly researched examples including alcohols (such as ethanol), fatty acids, polyalcohols, pyrrolidone, amines, amides, dimethyl sulfoxide, sulfoxides, esters, water, terpenes, surfactants, and others [284]
As of June 2025, the FDA removed both semaglutide and tirzepatide from its drug shortage list, a move that limits when and how pharmacies can legally compound these medications
Many people who take semaglutide, especially those who adopt lifestyle changes, can maintain their ideal weight with the lowest effective dose of the medication
Industry pays tribute Commentary from the health and wellness industry poured in after the news broke