Frequency depends on the formula, your goals, and your providers guidance
Summary: True vitamin B12 overdose is exceptionally rare because it is water-soluble and excess amounts are excreted through urine rather than accumulating in body tissues
Try sipping small amounts frequently rather than drinking large volumes at once, choose room temperature fluids instead of very cold water, and consider electrolyte solutions, herbal teas (ginger or peppermint), clear broths, or water-rich foods like watermelon
Published peer-reviewed studies include research on transected Achilles tendons in rats, quadriceps muscle crush injury models, surgically-induced and chemically-induced gastrointestinal lesions, NSAID-induced mucosal damage models, and ligament transection recovery studies
Moreover, its shortcomings have been linked to disturbed homocysteine metabolism, which is associated with various conditions including cancer and cardiovascular disease [52, 53]
Its very rare to have high levels of B12