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And that matters

Erratum in: Med Sci Sports Exerc

10.1089/jmf.2007.634 117 JainS.SinghS

It restores the physical transport mechanism required for the electron relay race to continue

doi: 10.1210/en.2010-0289

So the tetrasubstituted core is three stability modifications plus one potency modification, bundled together and usually described as though all four were the same kind of fix