Dermatology are very professional, warm and friendly
The regain problem The main theory for why the majority of patients regain weight so rapidly when they stop taking medication is because the regions of the brain relating to appetite are still dysregulated, priming the person to overconsume
This concept by no means is incompatible with the finding that inhibition of GCGR signalling also results in alpha cell proliferation but we emphasise that the latter effect operates on a much longer time scale than the acute effect we now describe (days/weeks rather than minutes/hours)
Because sustainable fat loss is not simply about eating less
It contains three patented, plant-based ingredients, each with its own small clinical study behind it: Eriomin (lemon bioflavonoids): shown to slightly increase natural GLP-1 levels in people with elevated blood sugar [1] Supresa (saffron extract): linked to reduced snacking in mildly overweight women, although some studies found no significant effects on food cravings [2][3] Morosil (red orange extract): found to support mild fat loss over 12 weeks [4] All three ingredients are studied independently , not as a combined formula
Dual GLP1 and GIP agonists Tirzepatide is a once weekly, subcutaneous, unimolecular dual RA (GLP-1 and GIP) which has comparable GIP receptor binding affinity to native GIP and 5 times lower GLP-1 receptor affinity than that of native GLP-1