6F, the response value of CIA mice in both the saline and the MCMs groups decreased to approximately 2.0 g in the von Frey test and to 4 s in the hot plate test, indicating a pain-sensitive phenotype of chronic inflammation
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Considering that the use of metformin and simvastatin led to increased apoptosis and decreased mitochondrial membrane potential in glioma cell lines, we speculate whether these two drugs cause DNA damage in glioma cells
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Metabolite addback and inhibitor treatment experiments were performed in the media conditions listed with supplementation of the listed metabolite or drug with equal volumes of vehicle control unless otherwise specified
Immunoaffinity purification of acetylated peptides IMAC flowthrough fractions were concatenated into four fractions, reconstituted in immunoaffinity purification (IAP) buffer and incubated with anti-acetyllysine antibody beads (Cell Signaling PTMScan)