The most common side effects include nausea affecting 15-44% of users, diarrhea in 10-30%, vomiting in 7-25%, and constipation in 6-24%
A recent study showed that adults with type 2 diabetes who ate a mixed evening meal with skinless potatoes had a reduced overnight glycemic response compared to those who ate a meal containing low-GI basmati rice
Pen or tablet: use the product-specific prescription directions and Instructions for Use
So EGF is a plausible cell-renewal signal with a real mechanism, not a guaranteed pigment shield, and a randomized controlled trial of microneedling combined with topical growth factors did report improvements in skin parameters with no adverse effects, which supports the pairing of needling and growth-factor delivery while stopping well short of overpromising
[PubMed: 27671968] Molinoff PB, et al
This section is arguably the most practically important part of this entire guide, because GI side effects are the primary reason people discontinue either medication