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See all articles Overview Semaglutide and tirzepatide are peptides similar to two hormones produced by the digestive system, namely glucagon-like peptide-1 (GLP-1) and glucosedependent insulinotropic polypeptide (GIP)

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In participants with obesity or overweight, withdrawing tirzepatide led to substantial regain of lost weight, whereas continued treatment maintained and augmented initial weight reduction [75]

The review also documented improvements in psychological and behavioural factors, such as reductions in food craving and emotional eating, as well as lowered scores on questionnaires about binge severity

Insulin action and insulin resistance: diseases involving defects in insulin receptors, signal transduction, and the glucose transport effector system 1

by Richard Weil, M.Ed., CDE Founder and Director Transformation Weight Control I like to show the following slide when discussing side effects of GLP-1 receptor agonists