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Older adults frequently need higher vitamin B12 intake because gastric acid production decreases with age, reducing the release of B12 from food proteins

Many protocols don't use daily administration

Vitamin D is an essential fat-soluble vitamin

Immunofluorescence results showed a significant increase in FOXO4 and p53bp1 foci within the nucleus of senescent cells compared to those in dividing cells (Figure

However, our results showed that no significant upregulation were observed after treatment with various copper compounds (SI1)

[2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly people who have renal insufficiency, [28] and elevated homocysteine is not conclusive, as it is also seen in people with folate deficiency