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This EV-mediated transfer of mtDNA may amplify neuroinflammatory responses by activating PRR in recipient cells, thereby facilitating the spread of pathological signals across neural networks

10.1038/s41590-020-00849-2 35 GuilliamsM.ThierryG

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The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency

1 Introduction Microorganisms derived from both the maternal body and the external environment begin to colonize the intestine at birth, progressively forming a structurally stable community known as the GM ( In 1976, esteemed researcher Genant et al