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This method is highly effective in the treatment of local problems such as wrinkles, scars and skin tone irregularities

The inoculation volumes were adjusted to an initial OD 600 of 0.15 in 200 mL baffled Erlenmeyer flasks and cultured at 200 rpm in a shaking incubator (BR-43FL, TAITEC, Saitama, Japan) at 30 C

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Apply creamSmooth an even layer over the face and neck, avoiding the eyes