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Things like a serious infection or injury, and diseases like uncontrolled hypertension and diabetes, can cause acute or chronic nephritis, which affects both kidneys and the million filtering units in each

Aggressive force, rapid injection, or vigorous agitation can disrupt this structure through a process called mechanical denaturation

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This is especially important for people with existing medical risks or limited lab monitoring

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Mitochondria also host antioxidant enzymes such as superoxide dismutase (SOD) and catalase as the first line of defense against ROS by converting superoxide to H 2 O 2 and subsequently to water