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There are two major pathways through which apoptosis are induced, but both pathways converge on caspase-3 activation, resulting in nuclear degradation and cellular morphological change 49

Nurliyani, N., Harmayani, E., & Sunarti, S

Generally, this treatment is recommended for those with a BMI of 27 or higher

Furthermore, challenges such as low drug concentration at the local pathological site after systemic administration, limited target specificity and short drug half-life persist [6]

Adjust dosages under medical supervision and track the transition to ensure a smooth switch