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These adverse events lead some patients to discontinue therapy before achieving optimal clinical outcomes, reducing long-term treatment adherence

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Weight reduction triggers adaptive changes in hunger and satiety hormones and energy expenditure, which favor weight regain, Neff says

doi: 10.1016/j.cgh.2013.11.031

Kennedy has already insinuated that the use of GLP-1s in children could raise the specter of unforeseen problems that interrupt, damage, or impair metabolism and growth development, in his controversial MAHA Report