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Some studies show that mixed therapy is beneficial to all patients, but the addition of lyothyronine causes side effects, so the medication should be evaluated on an individual basis

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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Miyawaki K, et al

However, many genes identified by genome-wide MR analyses lack clear pharmacological tractability

10.1039/d4ra02336f 59 LiC.CuiK.ZhuX.WangS.YangQ.FangG

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