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Accessed 09 Jun 2020

Juniper, E.T., Firth, P.A., Hargreave, F.E., Airway responsiveness to histamine and methacholine: Relationship to minimum treatment to control symptons of asthma, Thorax 36:575 (1981)

In vitro and preclinical in vivo experiments in arthritis have uncovered weight-loss-independent anti-inflammatory and chondroprotective properties of GLP-1RAs

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However, DON has had difficulty progressing into clinical trials due to concerns regarding its lack of selectivity to GLS and toxicity [110, 113, 114]

Docking results revealed a binding energy of 4.0 kcal/mol, which corresponds to a calculated inhibition constant (Ki) of approximately 1180 M, indicating weak inhibitory activity