Compared with the control group, the triglyceride (TG) content was significantly decreased in the carnitine supplementation group in the liver and muscle in both the feeding and fasting states
Total and LDL cholesterol levels increased in the L-carnitine group, and L-carnitine supplementation was also associated with 9.3% greater carotid arterial plaque stenosis in males who ate less red meat and had lower baseline stenosis and total plaque volume than other participants.26 A 2018 study including participants on a nonvegetarian diet found that 24 weeks of supplementation with 1,500 mg of L-carnitine increased fasting blood levels of carnitine and increased levels of TMAO tenfold but did not increase lipids, inflammatory markers, or other markers of atherosclerosis in healthy, omnivore, nonsmoking, physically active women ages 65 to 70 when compared with placebo
Kekic offers a framing for this from her clinical practice
Reducing fat-driven inflammation Fat tissue releases inflammatory chemicals
It is really quite backward
Liver Health: The supplement may have hepatoprotective effects, meaning it could help protect the liver