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For many supplements, current research results are mixed or preliminary, indicating a need for further investigation
The study enrolled 30 children with ASD (19 males and 11 females) diagnosed according to DMS-V and confirmed through ADOS/ADI-R, while excluding those with neurodevelopmental comorbidities, chronic medical conditions, gastrointestinal diseases, or special diets
The secretion of incretin hormones from enteroendocrine cells in the gut epithelium, including glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), potentiates postprandial insulin secretion, a phenomenon known as the incretin effect
Semaglutide is associated with a well-established profile of gastrointestinal adverse effects, which occur in a substantial proportion of users
( 2 ) Statement of Life Sciences and Medical Ethics: All procedures followed the guidelines of the National Health and Medical Research Council of China and received approval (GIBH-LMEC2024-091-01(AL)) from the Committee on Life Sciences and Medical Ethics of Guangzhou Institutes of Biomedicine and Health, CAS for the project [Research on the Mechanism of stem Cell Therapy in the mouse Autism Model Induced by VPA] on [August 15, 2024]
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