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While excess weight is a risk factor, its not the primary cause

"Assessing oxidative pathway genes as risk factors for bipolar disorder"

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For the most part, hematology and plasma biochemistry findings are unremarkable, although a combination of findings may increase clinical suspicion

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For example, long-term exercise from adulthood to old age induces anti-inflammatory effects, which is indicated by decreased level of inflammatory biomarkers, including white blood cell and neutrophil counts, IL-6, IL-10, IL-1 receptor antagonist, and soluble tumor necrosis factor receptor-1 (Moore et al., 2012)