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MenSCs also contribute to neural repair by attenuating glial scar formation, as evidenced by the reduced expression of inhibitory molecules such as chondroitin sulfate proteoglycans (CSPGs) ( Hjazi and colleagues (Zhao et al., 2021)

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For individuals with adequate B12 levels , supplementation is unlikely to provide additional energy or affect sleep patterns

f , Relative fold change of growth for Huh7 cells treated with indicated concentrations of R162 and -KG for 72 h

The nutrient is conditionally essential because the body produces it, however without enough, there can be serious consequences

Notably, supplementation with ferrostatin-1 or trolox, both of which are radical-trapping antioxidants and potent inhibitors of ferroptosis, rescued survival but not proliferation under cystine-free conditions (Extended Data Fig