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In the context of inflammatory skin diseases, oxidative stress can disrupt the skin's hydrolipid barrier, damage keratinocyte DNA, oxidize lipids in the stratum corneum, and induce the production of pro-inflammatory cytokinesinterleukin-1 (IL-1) and interleukin 33 (IL-33)in the dermis, promoting inflammation and exacerbating the disease (120)

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B Vitamin Supplements for PCOS There are several types of B vitamins, but the most important for PCOS patients are vitamin B12 and folate (B9)

The production of melanin is driven by an enzyme called tyrosinase