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Therefore, additional research is warranted to explore the potential application of nanoparticle-loaded drugs for the treatment of kidney diseases

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Likewise, ChREBP knockout protected against fructose-induced steatosis in mice, but substantially increased histological liver damage as a result of enhanced cholesterol synthesis and subsequent cytotoxicity [50]

As reference, we also measured the expression of spxB (encodes for the pyruvate oxidase) [32, 33] and sodA (encodes for a superoxide dismutase) [6] that increased their transcript levels in response to H 2 O 2 , as reported for aerobic conditions [5]

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