In addition to promoting GH secretion (Kojima et al., 1999), the ghrelin-ghrelin receptor system participates in appetite stimulation, body temperature regulation, and cardioprotection ( Acyl-modified hormone: ghrelin Ghrelin, a peptide hormone isolated and purified from the rat stomach in 1999, is a endogenous ligand of the GHS receptor (now referred to as the ghrelin receptor) (Kojima et al., 1999)
So once again, if youre deciding on a GLP-1, is the patient starting to do the right stuff
The authors of the same publication suggest this could be attributed to increased food intake and improved nutrient digestibility
metabolism and bioenergetics
A 10-year study of 1390 adults reported that AMD was 53% more common in subjects with high blood homocysteine (over 15 mol/L), 89% more common in subjects with folate deficiency (below 11 nmol/L), and 82% more common in subjects with low vitamin B12 (below 185 pmol/L) (Gopinath 2013)
Chen M, Lyu Y, Zhao J, Han X, Huang T, Yang T, et al