Dec 15, 2025, 07:01 ET Wegovy (semaglutide injection) granted conditional marketing authorization for the treatment of non-cirrhotic metabolic dysfunction-associated steatohepatitis (MASH) in adults with moderate to advanced liver fibrosis (consistent with stages F2 to F3 fibrosis)
The study titled Off-label antiobesity treatment in patients without diabetes with GLP-1 agonists in clinical practice and published in Hormone and Metabolic Research indicates that 58% of patients reported side effects mostly concerning the gastrointestinal tract. In addition, more than 20% of the participants quit the drug because of intolerable side effects. This study certainly put Novo Nordisk on risk of bowel injuries associated with the use of Ozempic
47,50 Although phentermine/topiramate is licensed in the US, it received a negative opinion for the European Committee for Medicinal Products for Human Use (CHMP) due to concerns about the phentermines long-term impact on the heart and blood vessels, as well as the potential for psychiatric and cognitive effects
[DOI] [PubMed] [Google Scholar] 66.Ribas V., Garca-Ruiz C., Fernndez-Checa J.C
Il diminue galement le risque dvnements cardiovasculaires et aide la perte de poids
/ with their combination (L-NAME + NaBPC157, L-NAME + L-arginine))
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