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Multiple sclerosis MS involves autoimmune destruction of myelin in the central nervous system, leading to progressive neurological disability

10.1001/jamaneurol.2014.131 JAMA Neurol

The role of metformin on vitamin B12 deficiency: a meta-analysis review. Internal and emergency medicine 10 (2015): 93-102

The result is selective fat tissue activation without any central nervous system effects on eating behavior

Reported side effects include mild headaches or dizziness (more common when combined with growth hormone peptides), injection site irritation, GI discomfort from low-quality oral preparations, and occasional mood or energy changes