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The starting dose in patients already treated with metformin should provide sitagliptin dosed as 50 mg twice daily (100 mg total daily dose) and the dose of metformin already being taken

Things like FDA approval, doctor support, medication format, and pharmacy quality all matter and should be considered before deciding

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eGLP-1 showed a markedly lower potency at both human and platypus receptors that was even lower than OXM

One potential drawback associated with GLP-1 medications is that weight loss not only includes fat loss, but muscle loss as well, with some studies finding that about 30% of the weight loss from GLP-1s may be contributed to loss of lean mass, or muscle mass