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Cardiovascular diseases (CVDs) are the leading cause of mortality post-transplant, driven by prevalent traditional risk factors, along with complications related to chronic kidney disease (CKD), such as left ventricular hypertrophy and mineral bone disease, which often persist after the transplant [3, 4]

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Furthermore, we observed the expression of the well-known membrane-associated FNDC5 and a novel, secretable FNDC5 (sFNDC5) isoform in cells and multiple rat tissues