However, the BfR recommends limiting the daily intake to a maximum of 9 g, i.e
(30921021) Half-life : 9-19 hours
Another possibility is the following: after uptake, vitamin B12 is slowly bound to serum vitamin B12 proteins ( The mechanism by which vitamin B12 administration exerts its positive effect on ME/CFS patients is unknown
Concurrent use of medications that affect b12 absorption Several common medications interfere with b12 absorption through various mechanisms
One prominently cited case report promotes the use of total body weight, but I wouldnt recommend this
Vitamin B12 Injection Dose for Children For children with vitamin B12 deficiency, an initial dose of 0.2 mcg/kg injected into the muscle or under the skin daily for 2 days, followed by daily 1000 mcg injections for 2-7 days, then weekly 100 mcg injections for 4 weeks, may be recommended