J., Stine, Z
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Additional caution or monitoring may be appropriate in research settings involving: Active cancer- or tumor-related research models, where antioxidant-related pathways may influence cellular-response or treatment-response mechanisms Severe asthma or hypersensitivity-prone research models, as rare sensitivity-related observations have been reported in some experimental contexts Sulfur-sensitive research models, due to Glutathione containing a thiol (sulfur-containing) group Complex hepatic-function or detoxification-related investigations, where antioxidant modulation may influence oxidative-stress or liver-related biomarkers Research conditions, research amounts, protocol duration, administration frequency, and concurrent compounds may influence tolerability observations across experimental settings
Proton pump inhibitors (PPIs) and H2-receptor antagonists reduce gastric acid production, impairing the release of B12 from dietary proteinsthough intrinsic factor-mediated absorption of synthetic B12 remains largely intact
10.1038/mi.2014.35 8 ChenJ.XuF.RuanX.SunJ.ZhangY.ZhangH.et al (2023a)
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