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One hour later, rats were anesthetized with ketamine (90 mg/kg), xylazine (2.8 mg/kg), and acepromazine (0.72 mg/kg) and transcardially perfused with 0.1 M phosphate-buffered saline (PBS) followed by 4% paraformaldehyde (PFA) in PBS

(2001) preclinical study (PMID 11285201) demonstrating that the C-terminal fragment of hGH (residues 177-191, the basis of AOD-9604) inhibits fat cell formation in 3T3-L1 cells, establishing the rationale for AOD-9604 as a lipolytic agent

Ongoing Phase 3 Trials Phase 3 trials are currently underway as part of the TRIUMPH clinical trial program, enrolling thousands of participants across multiple studies examining retatrutide for obesity, type 2 diabetes, obesity-related complications, and MASH